Complete Information on Acidemia propionic with Treatment and Prevention
Propionic Acidemia is inherited as an autosomal recessive trait.
Acidemia propionic is an organic aciduria produced by the deficiency of propionyl CoA-carboxylase, producing a ketotic hyperglycinemia and recurrent metabolic imbalance. In this disorder the body is unable to process certain parts of proteins and lipids properly. The condition appears to be more common in several populations worldwide, including the Inuit population of Greenland, some Amish communities, and Saudi Arabians. Death can occur quickly, due to secondary hyperammonemia, infection, cardiomyopathy, or basal ganglial stroke. Acidemia propionic is characterized almost immediately in newborns. Symptoms include poor feeding, vomiting, dehydration, acidosis, low muscle tone, seizures, and lethargy. The effects of propionic acidemia quickly become life-threatening.
