Eisenmenger syndrome usually develops before puberty but may develop in adolescence and early adulthood. Eisenmenger syndrome occurs in patients with big inborn cardiac or surgically created extracardiac left-to-right shunts. These shunts initially induce increased pulmonary blood flowing. People who have Eisenmenger’s syndrome are normally born with a big hole in the eye. The most common situation is a hole between the two pumping chambers, called a ventricular septal defect. Usually, Eisenmenger syndrome develops while individuals with heart defects are still children, but it may occur in adolescence or young adulthood. A number of congenital heart defects can cause Eisenmenger’s syndrome, including atrial septal defects, ventricular septal defects, patent ductus arteriosus, and more complex types of acyanotic heart disease.
Bipolar disorder, also known as manic depression, is characterized by cycling mood changes, with episodes of depression alternating with episodes of mania.
As collagen is an important protein in bone structure, this impairment causes those with the condition to have weak or fragile bones. Brittle bone disease syndrome also known as osteogenesis imperfecta. Osteogenesis imperfecta” means imperfect bone formation. People with this condition have bones that break easily, often from mild trauma or with no apparent cause. People with OI are born without the proper protein (collagen), or the ability to make it, usually because of a deficiency of Type-I collagen. People with OI either have less collagen than normal or the quality is poorer than normal. |